Investigate value of CCTA in guidance of CTO PCI procedures.Investigate prognostic value of CT-derived plaque characteristics for occurrence of MACE following bypass graft PCI.PCI of dysfunctional venous bypass graft with a clinical indication for revascularisation Investigate the clinical outcome of native vessel PCI vs. Study objectives:to investigate the clinical and angiographic outcome of native vessel PCI compared to PCI of venous bypass graft in patients with a dysfunctional venous bypass graft with a clinical indication for revascularization. No additional study procedures will be performed. Patients will be followed by telephonic follow-up after 1, 3, and 5 years. Written informed consent is mandatory for participating in the registry. Patients will be approached for participation and will have one week to consider. the patient does not meet the in- and exclusion criteria for the randomized PROCTOR study or declines to participate in the randomized study.both the lesions in the native vessel and the dysfunctional graft have been deemed technically feasible by the local hartteam,.
PCI have been deemed clinically indicated by the local hartteam, and.Patients can be approached for the registry when : The CCTA will be performed before the PCI procedure. After written informed consent is obtained patients will undergo a CCTA in an out-patient setting.
Participation in this substudy is optional. The CT-substudy and the PROCTOR registry is planned to be conducted too (details included in the flow chart).ĬCTA substudy Selected patients will be approached for participation in the CCTA substudy of the trial. Patients with a dysfunctional bypass graft with a clinical indication for revascularization will be randomized to either PCI of the native vessel or PCI of the dysfunctional venous bypass graft.
NATIVE VESSEL MEANING TRIAL
Multi-centre, randomised clinical trial with anticipated 17 European centres: in the Netherlands, Belgium, Germany and UK. Procedure: Percutaneous coronary intervention After 3 years patients will be admitted to undergo a control invasive angiography.The CT-substudy and the PROCTOR registry is planned to be conducted too. 1 year and 5 years, follow-up will be performed by means of a telephonic visit. 584 patients with a a clinical indication for percutaneous coronary intervention and a dysfunctional graft on the target vesselional venous bypass graft are planned to be enrolled during 3 years.Study objectives: to investigate the clinical and angiographic outcome of native vessel PCI compared to PCI of venous bypass graft in patients with a dysfunctional venous bypass graft with a clinical indication for revascularization.